Summary: Glecaprevir/Pibrentasvir Treatment Failures
Recommended regimens listed by evidence level and alphabetically for:
Glecaprevir/Pibrentasvir Treatment Failures (All Genotypes), With or Without Compensated Cirrhosisa 
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RECOMMENDED
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DURATION
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RATING 
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Daily fixed-dose combination of glecaprevir (300 mg)/pibrentasvir (120 mg) plus daily sofosbuvir (400 mg) and weight-based ribavirin
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16 weeks
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IIa, B
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Daily fixed-dose combination of sofosbuvir (400 mg)/velpatasvir (100 mg)/voxilaprevir (100 mg)
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12 weeks
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IIa, B
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For patients with compensated cirrhosis, addition of weight-based ribavirin is recommended.
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12 weeks
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IIa, C
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a For decompensated cirrhosis, please refer to the appropriate section.
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