Overview
The following pages include guidance for management of persons with HCV in unique and key populations.
Unique Populations
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HCV in Children
Testing Recommendations for HCV Testing of Perinatally Exposed Children and Siblings of Children With HCV Infection RECOMMENDED RATING All children…
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HCV in Pregnancy
Testing Recommendation for Universal Hepatitis C Screening in Pregnancy RECOMMENDED RATING As part of prenatal care, all pregnant persons should…
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Kidney Transplant Recipients
Post Kidney Transplantation: Genotype 1-6 Recommended and alternative regimens listed by pangenotypic, evidence level and alphabetically for: Treatment-Naive and Non-DAA-Experienced…
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Management of Acute HCV Infection
Acute hepatitis C infection is most often asymptomatic and frequently develops into chronic infection. Case reports of acute hepatitis C…
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Persons Who Develop Recurrent Hepatitis C Post Liver Transplantation
Post Liver Transplantation: Genotype 1-6 Recommended regimens listed by pangenotypic activity, evidence level, and alphabetically for: Treatment-Naive and Treatment-Experienced Persons With Genotype…
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Persons With Decompensated Cirrhosis
Recommended for All Persons With HCV Infection Who Have Decompensated Cirrhosis RECOMMENDED RATING Persons with HCV infection who have decompensated…
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Persons With Hepatocellular Carcinoma
Hepatitis C virus (HCV) infection is a leading cause of hepatocellular carcinoma (HCC) (Fiehn, 2024). Attention to the subpopulations of individuals…
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Persons With HIV/HCV Coinfection
This section provides guidance on the treatment of chronic HCV infection in people living with HIV. For guidance regarding management…
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Persons with Renal Impairment
Chronic hepatitis C is independently associated with the development of chronic kidney disease (CKD) (Rogal, 2016); (Fabrizi, 2015). A meta-analysis demonstrated…
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Treatment of HCV-Uninfected Transplant Recipients Receiving Organs From HCV-Viremic Donors
With the large disparity between persons in need of organ transplantation and available donor organs, many transplant programs are turning…
Key Populations
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HCV in Key Populations: Identification and Management of HCV Infection in People Who Inject Drugs
Prevalence of HCV Among People Who Inject Drugs Injection drug use (IDU) is the most common risk factor for HCV…
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HCV in Key Populations: Men Who Have Sex With Men
Incidence and Risk Factors for HCV Infection Among Men Living With HIV Infection Who Have Sex With Men Several outbreaks of sexually transmitted HCV infection among men living with…
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HCV Testing and Treatment in Incarceration Settings
Prevalence of HCV Infection in Incarceration Settings HCV infection disproportionately affects individuals in incarceration facilities, which include jails (short-stay facilities that…
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Management of Key Populations With Chronic HCV Infection
People who inject drugs, men who have sex with men (MSM), and incarcerated persons bear a particularly high burden of chronic HCV…
