Overview
The following pages include guidance for management of patients with HCV in unique and key populations. Unique populations include those with liver and nonliver related comorbidities, acute HCV infection, pregnant people and children. Key populations include people who may be at higher risk of HCV infection and may require additional considerations in diagnosis and management.
Unique Populations
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HCV in Children
Testing Recommendations for HCV Testing of Perinatally Exposed Children and Siblings of Children With HCV Infection RECOMMENDED RATING All children…
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HCV in Pregnancy
Testing Recommendation for Universal Hepatitis C Screening in Pregnancy RECOMMENDED RATING As part of prenatal care, all pregnant persons should…
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Kidney Transplant Patients
Post Kidney Transplantation: Genotype 1-6 Recommended and alternative regimens listed by pangenotypic, evidence level and alphabetically for: Treatment-Naive and Non-DAA-Experienced…
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Management of Acute HCV Infection
Acute hepatitis C infection is most often asymptomatic and frequently develops into chronic infection. Case reports of acute hepatitis C…
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Patients Who Develop Recurrent HCV Infection Post Liver Transplantation
Post Liver Transplantation: Genotype 1-6 Recommended regimens listed by pangenotypic activity, evidence level and alphabetically for: Treatment-Naive and -Experienced Patients…
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Patients With Decompensated Cirrhosis
Recommended for All Patients With HCV Infection Who Have Decompensated Cirrhosis RECOMMENDED RATING Patients with HCV infection who have decompensated…
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Patients With HIV/HCV Coinfection
This section provides guidance on the treatment of chronic HCV infection in HIV/HCV-coinfected patients. For guidance regarding HIV/HCV-coinfected individuals with…
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Patients with Renal Impairment
Chronic hepatitis C is independently associated with the development of chronic kidney disease (CKD) (Rogal, 2016); (Fabrizi, 2015). A meta-analysis demonstrated…
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Treatment of HCV-Uninfected Transplant Recipients Receiving Organs From HCV-Viremic Donors
With the large disparity between patients in need of organ transplantation and available donor organs, many transplant programs are turning…
Key Populations
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HCV in Key Populations: Men Who Have Sex With Men
Incidence and Risk Factors for HCV Infection Among HIV-Infected Men Who Have Sex With Men Several outbreaks of sexually transmitted…
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HCV Testing and Treatment in Correctional Settings
Prevalence of HCV infection in Correctional Settings HCV infection disproportionately affects individuals in correctional institutions, which include jails (short-stay facilities…
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Key Populations: Identification and Management of HCV in People Who Inject Drugs
Prevalence of HCV Among People Who Inject Drugs Injection drug use (IDU) is the most common risk factor for HCV…
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Management of Key Populations With Chronic HCV Infection
People who inject drugs (PWID), men who have sex with men (MSM), and individuals in jails and prisons bear a…