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HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C
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Table of Contents
Test, Evaluate, Monitor
Treatment-Naive Patients
Treatment-Experienced Patients
Unique & Key Populations
About the Guidance
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Table of Contents
Introduction
Methods
Methods Table 1
Methods Table 2
Methods Table 3 Abbreviations
References
Test, Evaluate, Monitor
Testing and Linkage to Care
When and in Whom
Cost, Reimbursement, and Cost-Effectiveness
Monitoring
HCV Resistance
Treatment-Naive
Treatment Simplification
Genotype 1
GT1a: No Cirrhosis
GT1a: Compensated
GT1b: No Cirrhosis
GT1b: Compensated
Genotype 2
GT2 : No Cirrhosis
GT2 : Compensated
Genotype 3
GT3 : No Cirrhosis
GT3 : Compensated
Genotype 4
GT4 : No Cirrhosis
GT4 : Compensated
Genotype 5 or 6
Treatment-Experienced
Genotype 1
GT1a : P/R : No Cirrhosis
GT1a : P/R : Compensated
GT1b : P/R : No Cirrhosis
GT1b : P/R : Compensated
GT1 : NS3 : No Cirrhosis
GT1 : NS3 : Compensated
GT1 : Non-NS5A : No Cirrhosis
GT1 : Non-NS5A : Compensated
GT1 : NS5A
All GT: G/P
All GT: SOF/VEL/VOX
Genotype 2
GT2 : P/R : No Cirrhosis
GT2 : P/R : Compensated
GT2 : DAA
All GT: G/P
All GT: SOF/VEL/VOX
Genotype 3
GT3 : P/R : No Cirrhosis
GT3 : P/R : Compensated
GT3 : DAA
All GT: G/P
All GT: SOF/VEL/VOX
Genotype 4
GT4 : P/R : No Cirrhosis
GT4 : P/R : Compensated
GT4 : DAA
All GT: G/P
All GT: SOF/VEL/VOX
Genotype 5 or 6
GT 5 or 6 : P/R
GT 5 or 6 : DAA
All GT: G/P
All GT: SOF/VEL/VOX
Unique & Key Populations
HIV/HCV Coinfection
Decompensated Cirrhosis
Post Liver Transplant
Renal Impairment
Kidney Transplant
Acute Infection
HCV in Pregnancy
HCV in Children
PWID, MSM & Corrections
People Who Inject Drugs
Men Who Have Sex With Men
Correctional Settings
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Oluwaseun O. Falade-Nwulia, MBBS, MPH
Assistant Professor of Medicine
Johns Hopkins University School of Medicine
Baltimore, MD, USA
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